Trimix Injection TherapyThe Most Effective ED Treatment
Trimix injection therapy is the most effective treatment for erectile dysfunction, with a 98% success rate—significantly higher than oral medications like Viagra (60-70%). Works in 5-10 minutes regardless of nerve damage or vascular issues.
What is Trimix Injection Therapy?
Trimix is a prescription compounded medication combining three vasodilators that work together to produce reliable erections in 98% of men, including those who don't respond to oral ED medications like Viagra or Cialis.
Alprostadil (Prostaglandin E1)
Relaxes smooth muscle and dilates blood vessels in erectile tissue
Papaverine
Increases blood flow by relaxing arterial walls
Phentolamine
Blocks receptors that constrict blood vessels
Together, these medications produce reliable erections in 98% of men. If you're wondering what to do when pills stop working, Trimix injection therapy is often the answer.
What is Bi-Mix?
Bi-Mix is a two-ingredient alternative to Trimix, containing papaverine and phentolamine (without alprostadil). It's often used as a starting point for men new to injection therapy. Many patients begin with Bi-Mix and progress to Trimix if a stronger effect is needed.
Bi-Mix
- • Two medications (papaverine + phentolamine)
- • Good starting point for new patients
- • Lower potency, fewer side effects
- • Often sufficient for mild-moderate ED
Trimix
- • Three medications (adds alprostadil)
- • Maximum effectiveness
- • 98% success rate
- • Works for severe ED and treatment-resistant cases
How Trimix Injection Therapy Works
Trimix works through direct injection into the corpus cavernosum (erectile tissue):
Medication injected using fine 30-gauge needle (similar to insulin)
Three medications relax smooth muscle tissue within 5-10 minutes
Blood flows into the penis, producing a firm erection
Erection lasts 30-60 minutes (dose-dependent)
Erection subsides naturally as medication metabolizes
Trimix vs Viagra: How They Compare
| Factor | Trimix Injection | Viagra/Cialis |
|---|---|---|
| Success Rate | 98% | 60-70% |
| Time to Work | 5-10 minutes | 30-60 minutes |
| Requires Arousal | No | Yes |
| Works with Nerve Damage | Yes | Often No |
| Works with Vascular Disease | Yes | Limited |
| Duration | 30-60 minutes | 4-36 hours |
Why Injection Therapy Works When Pills Fail
Oral ED medications require intact nerve pathways and adequate blood flow to work. Injection therapy bypasses both requirements:
Direct Action
Medication works directly on erectile tissue, not through nerve signals
Independent of Blood Flow
Creates local vasodilation regardless of systemic vascular health
No Arousal Required
Produces erection mechanically, not dependent on sexual stimulation
Works with Diabetes
Effective even with diabetic nerve and vascular damage
Works After Surgery
Effective for men with nerve damage from prostate surgery
Learn more about all erectile dysfunction treatments or explore shockwave therapy as a complementary option.
Getting Started with Injection Therapy
From your first consultation to at-home treatment, we guide you every step of the way.
Consultation & Evaluation
Our physician evaluates your health history and determines the optimal medication blend for your needs.
Dosage Calibration
We start with a low dose and adjust to find your perfect dosage that provides reliable results.
Self-Injection Training
Our medical team teaches you the proper injection technique. Most men find it painless after the first time.
At-Home Treatment
Take your prescription home and enjoy spontaneous intimacy whenever you choose.
Safety & Side Effects
ED injection therapy is well-tolerated by most men. Potential side effects include:
Common (Mild)
- • Minor bruising at injection site
- • Temporary aching during erection
- • Small nodules (with repeated use)
Rare (Requires Attention)
- • Prolonged erection (priapism) - seek care if >4 hours
- • Significant pain or swelling
We provide detailed safety instructions and emergency protocols with every prescription. Most men use injection therapy safely for years.
Frequently Asked Questions
What is Trimix used for?
Trimix is used to treat erectile dysfunction (ED) in men who don't respond to oral medications like Viagra or Cialis. It's a compounded injectable medication containing three active ingredients—alprostadil, papaverine, and phentolamine—that work together to produce reliable erections with a 98% success rate.
How effective is Trimix for ED?
Trimix is the most effective ED treatment available, with approximately a 98% success rate. This is significantly higher than oral medications like Viagra and Cialis, which have 60-70% success rates. Trimix works even in men with diabetes, vascular disease, nerve damage, or those who have had prostate surgery.
Is Trimix better than Viagra?
For men who don't respond to Viagra, Trimix is significantly more effective. Trimix has a 98% success rate compared to Viagra's 60-70%. Trimix works through a different mechanism—directly relaxing smooth muscle tissue—so it's effective regardless of nerve function, arousal, or blood flow issues that may limit Viagra's effectiveness.
How long does Trimix last?
Trimix produces an erection within 5-10 minutes of injection that typically lasts 30-60 minutes. The exact duration depends on the dosage, which is calibrated to your individual needs. Your erection will subside naturally as the medication metabolizes.
Is injecting Trimix painful?
Most men report minimal discomfort—similar to a small pinch. We use very fine 30-gauge needles (the same size as insulin needles), and the injection site on the side of the penis has relatively few nerve endings. After the first injection, most patients say they barely feel it.
What are the side effects of Trimix?
Common side effects include minor bruising at the injection site and temporary aching. Rare but serious side effects include prolonged erection (priapism) lasting more than 4 hours, which requires immediate medical attention. We provide detailed safety protocols and emergency instructions with every prescription.
Can I get Trimix if Viagra doesn't work?
Yes, absolutely. Trimix is specifically designed for men who don't respond to oral ED medications. Our 98% success rate includes many men for whom Viagra and Cialis failed completely. During your consultation, we'll determine if Trimix is right for your situation.
ICP Injection Therapy Pricing
12-Month All-Inclusive Program
$2,850/year
- All medication included
- Syringes and supplies
- Training sessions
- Follow-up visits
90-Day Medication Supply
$300
For established patients who have completed training. Includes medication refill and supplies.
ICP Injection Therapy Locations
ICP injection therapy is available at our clinics in Green Bay, Wisconsin and Skokie, Illinois. We serve Appleton, Oshkosh, Chicago, Naperville, Evanston, Wilmette, and surrounding communities.
Ready to Experience Reliable Results?
Join the thousands of men who've found success with ED injection therapy. Schedule your free consultation today.
*98% Success Rate: Based on internal clinical study of penile injection therapy patients achieving erections sufficient for intercourse. Individual results may vary.